Is Azithromycin compatible with alcohol?
What to do if during the treatment I really want to use a glass of alcohol, a glass of wine, drink beer, and the doctor prescribed Azithromycin? If a person cares about his health, he will reflect on how Azithromycin and alcohol interact, is it safe for them to combine these elements and whether they can be drunk at the same time? The answer of doctors is unequivocal: alcohol and antibiotics are incompatible, so during treatment should avoid situations where there is a risk of drinking alcohol.
Effects from alcohol and Azithromycin
As most antibacterial medications, Azithromycin interacts with ethanol. That is why, the use of the antibiotic with alcohol is not recommended.
First, ethanol slows down the absorption of Azithromycin in the gastro-intestinal tract, and reduces its bioavailability. It means, that a concentration of the actual substances will be lower in the site of the infection, and it, of course, will reduce the intensity of the therapeutic effect.
Secondly, alcohol slows down metabolism, and it affects the metabolic processes of the actual substances. The therapeutic effect is also affected. The better the metabolism is during the treatment, the faster the morbific microorganisms are killed.
Thirdly, the interaction of Azithromycin with alcohol increases the load on the liver. As a result, the characteristics of the liver become worse during the use of the antibiotic with ethanol, and the liver may grow in size, the blood test will show it.
*Alcohol abuse during the use of any antibiotics threatens necrosis of the liver cells, and it may lead to cirrhosis.
Fourthly, a negative effect of the interaction of alcohol and Azithromycin affects the kidneys. The kidneys also take part in the metabolism of the antibiotics, and ethanol, and a renal failure may develop during the high load on the kidneys. It especially comes to the inflammatory processes when fever is observed. The load grows by three times.
The reaction of the liver and stomach
Especially strongly from the combination of "Azithromycin + alcohol" suffers the liver, which deals with the removal of toxins from the body, which is both an antibiotic and ethanol. In this case, the organ is under intense pressure, which can provoke the development of jaundice, the appearance of severe pain in the abdomen, and chronic fatigue.
Doctors advise to avoid everything that can make the liver work under stress, so it is believed that drinking alcohol with azithromycin is not the best choice for a person caring for their health.
Another result of the action of ethanol is the dehydration of tissues, which is especially pronounced during a hangover. If at this time to undergo therapy with Azithromycin, dehydration can exacerbate such side effects as nausea, vomiting, headache.
In addition, alcoholic beverages and this antibiotic are irritants of the gastrointestinal mucosa, to which the body can react with nausea, vomiting, convulsions, and abdominal pain. The combination of alcohol and Azithromycin intensifies these manifestations.
If it happened that during treatment alcohol was drunk, probiotics (eg, yogurt), enveloping substances are necessary. They restore the mucous and microflora to avoid excessive irritation.
Can I take antibiotics with alcohol?
The use of the antibiotics with alcohol is not recommended because severe adverse effects may occur. If a patient has a high sensitivity to Azithromycin or ethanol, the interaction of these ingredients may cause adverse effects: allergy, vomiting, nausea, and changed blood pressure.
If the symptoms of the alcohol intoxication pass within 2-3 days, the adverse effects are kept within several days during the combination of alcohol with the antibacterial drug. There are cases, when an infection process has turned into chronic because the antibiotic did not fully affected the originators because of alcohol.
However, there are studies and opinions that not all beverage drinks are dangerous during the interaction with the antibiotics. Strong alcoholic beverage (more than 9%) may cause disulfiram-like symptoms (we talked about them above). But such light beverage drinks as beer in low doses may not interact with the antibiotics.
However, doctors do not recommend to risk because a patient may not know about the issues with liver and kidneys. And these pathologies may become acute during the alcohol consumption, and the health problems may happen. Bear in mind that the antibiotics such as Azithromycin are kept in the blood within 3 days after the use of the last dose. It means that if you finished the treatment, it does not mean that you may take alcohol the next day.
At least 5-7 days should pass after the end of the antibacterial therapy for the full recovery of the body. Alcohol lowers immunity, and it may be dangerous after the disease.